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    Predictive model for Photodynamic Therapy with gold nanoparticles as vehicle for the photosensitizer delivery

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    Predictive model.pdf (745.4Kb)
    Identificadores
    URI: http://hdl.handle.net/10902/4688
    DOI: 10.1117/12.2031959
    ISBN: 978-0-8194-9652-2
    ISSN: 1996-756X
    ISSN: 0277-786X
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    Author
    Salas García, IreneAutoridad Unican; Fanjul Vélez, FélixAutoridad Unican; Ortega Quijano, NoéAutoridad Unican; Arce Diego, José LuisAutoridad Unican
    Date
    2013-05
    Derechos
    © 2013 Society of Photo-Optical Instrumentation Engineers and Optical Society of America. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
    Publicado en
    I. Salas-García, F. Fanjul-Vélez, N. Ortega-Quijano, and J. L. Arce-Diego, "Predictive model for Photodynamic Therapy with gold nanoparticles as vehicle for the photosensitizer delivery," in European Conference on Biomedical Optics: Medical Laser Applications and Laser-Tissue Interactions VI, L. Lilge and R. Sroka, eds., Vol. 8803 of Proceedings of OSA Biomedical Optics-SPIE, 88030N, (2013).
    Publisher
    The Optical Society (OSA)-
    SPIE Society of Photo-Optical Instrumentation Engineers
    Enlace a la publicación
    http://dx.doi.org/10.1117/12.2031959
    Palabras clave
    Photodynamic Therapy
    Gold nanoparticles
    Photosensitizer
    Basal cell carcinoma
    Abstract:
    Photodynamic Therapy offers multiple advantages to treat nonmelanoma skin cancer compared to conventional treatment techniques such as surgery, radiotherapy or chemotherapy. Among these advantages are particularly relevant its noninvasive nature, the use of non ionizing radiation and its high selectivity. However the therapeutic efficiency of the current clinical protocol is not complete in all the patients and depends on the type of pathology. Emerging strategies to overcome its current shortcomings include the use of nanostructures that can act as carriers for conventional photosensitizers and improve the treatment selectivity and provide a controlled release of the photoactive agent. In this work, a model for photodynamic therapy combined with gold nanocarriers for a photosensitizer commonly used in dermatology is presented and applied to a basal cell carcinoma in order to predict the cytotoxic agent spatial and temporal evolution.
    Collections to which it belong
    • D50 Congresos [429]
    • D50 Proyectos de Investigación [307]

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    UNIVERSIDAD DE CANTABRIA

    Repositorio realizado por la Biblioteca Universitaria utilizando DSpace software
    Contact Us | Send Feedback
    Metadatos sujetos a:licencia de Creative Commons Reconocimiento 3.0 España