Predictive analysis of optical ablation in several dermatological tumoral tissues
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AuthorFanjul Vélez, Félix; Blanco Gutiérrez, Andrea; Salas García, Irene; Ortega Quijano, Noé; Arce Diego, José Luis
© 2013 Society of Photo-Optical Instrumentation Engineers and Optical Society of America. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
F. Fanjul-Vélez, A. Blanco-Gutiérrez, I. Salas-García, N. Ortega-Quijano, and J. L. Arce-Diego, "Predictive analysis of optical ablation in several dermatological tumoral tissues," in European Conference on Biomedical Optics: Medical Laser Applications and Laser-Tissue Interactions VI, L. Lilge and R. Sroka, eds., Vol. 8803 of Proceedings of OSA Biomedical Optics-SPIE, 88030R, (2013).
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SPIE Society of Photo-Optical Instrumentation Engineers
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Optical propagation model
Monte Carlo method
Optical techniques for treatment and characterization of biological tissues are revolutionizing several branches of medical praxis, for example in ophthalmology or dermatology. The non-invasive, non-contact and non-ionizing character of optical radiation makes it specially suitable for these applications. Optical radiation can be employed in medical ablation applications, either for tissue resection or surgery. Optical ablation may provide a controlled and clean cut on a biological tissue. This is particularly relevant in tumoral tissue resection, where a small amount of cancerous cells could make the tumor appear again. A very important aspect of tissue optical ablation is then the estimation of the affected volume. In this work we propose a complete predictive model of tissue ablation that provides an estimation of the resected volume. The model is based on a Monte Carlo approach for the optical propagation of radiation inside the tissue, and a blow-off model for tissue ablation. This model is applied to several types of dermatological tumoral tissues, specifically squamous cells, basocellular and infiltrative carcinomas. The parameters of the optical source are varied and the estimated resected volume is calculated. The results for the different tumor types are presented and compared. This model can be used for surgical planning, in order to assure the complete resection of the tumoral tissue.
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