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dc.contributor.authorReal Peña, Eusebio 
dc.contributor.authorEguizabal Aguado, Alma 
dc.contributor.authorPontón Cortina, Alejandro 
dc.contributor.authorVal Bernal, José Fernando 
dc.contributor.authorMayorga Fernández, Marta María
dc.contributor.authorRevuelta Soba, José Manuel 
dc.contributor.authorLópez Higuera, José Miguel 
dc.contributor.authorConde Portilla, Olga María 
dc.contributor.otherUniversidad de Cantabriaes_ES
dc.date.accessioned2014-05-13T09:46:26Z
dc.date.available2014-05-13T09:46:26Z
dc.date.issued2013-05
dc.identifier.isbn978-0-8194-9651-5
dc.identifier.issn1996-756X
dc.identifier.issn0277-786X
dc.identifier.otherTEC2010-20224-C02-02es_ES
dc.identifier.otherFIS2010-19860es_ES
dc.identifier.urihttp://hdl.handle.net/10902/4622
dc.description.abstractOptical coherence tomographic images of ascending thoracic human aortas from aneurysms exhibit disorders on the smooth muscle cell structure of the media layer of the aortic vessel as well as elastin degradation. Ex-vivo measurements of human samples provide results that correlate with pathologist diagnosis in aneurysmatic and control aortas. The observed disorders are studied as possible hallmarks for aneurysm diagnosis. To this end, the backscattering profile along the vessel thickness has been evaluated by fitting its decay against two different models, a third order polynomial fitting and an exponential fitting. The discontinuities present on the vessel wall on aneurysmatic aortas are slightly better identified with the exponential approach. Aneurysmatic aortic walls present uneven reflectivity decay when compared with healthy vessels. The fitting error has revealed as the most favorable indicator for aneurysm diagnosis as it provides a measure of how uniform is the decay along the vessel thickness.es_ES
dc.description.sponsorshipThis work has been supported by the Spanish Government through CYCIT projects DA2TOI (FIS2010-19860), TFS (TEC2010-20224-C02-02) and the Alma’s Eguizabal PhD Grant (FPU12/04130)es_ES
dc.format.extent7 p.es_ES
dc.language.isoenges_ES
dc.publisherThe Optical Society (OSA)-es_ES
dc.publisherSPIE Society of Photo-Optical Instrumentation Engineerses_ES
dc.rights© 2013 Society of Photo-Optical Instrumentation Engineers and Optical Society of America. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.es_ES
dc.sourceE. Real, A. Eguizabal, A. Pontón, J. Fernando Val-Bernal, M. Mayorga, J. M. Revuelta, J. M. López-Higuera, and O. M. Conde, "Optical coherence tomography assessment of vessel wall degradation in aneurysmatic thoracic aortas", in European Conference on Biomedical Optics: Optical Coherence Tomography and Coherence Techniques VI, B. Bouma and R. Leitgeb, eds., Vol. 8802 of SPIE Proceedings, 88020G (2013)es_ES
dc.subject.otherOCTes_ES
dc.subject.otherAneurysm diagnosises_ES
dc.subject.otherAscending thoracic aortaes_ES
dc.subject.otherVessel walles_ES
dc.titleOptical coherence tomography assessment of vessel wall degradation in aneurysmatic thoracic aortases_ES
dc.typeinfo:eu-repo/semantics/conferenceObjectes_ES
dc.relation.publisherVersionhttp://dx.doi.org/10.1117/12.2032592es_ES
dc.rights.accessRightsopenAccesses_ES
dc.identifier.DOI10.1117/12.2032592
dc.type.versionpublishedVersiones_ES


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