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    Análisis automático de la posición y del número de plásmidos en una célula bacteriana

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    URI: http://hdl.handle.net/10902/3091
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    Author
    González de Aledo Marugán, PabloAutoridad Unican; Vielva Martínez, Luis AntonioAutoridad Unican; Vía Rodríguez, JavierAutoridad Unican; Guynet, Catherine; Meile, Jean-Christophe; Cruz Calahorra, Fernando de la
    Date
    2010-09
    Derechos
    © 2010 URSI España
    Publicado en
    URSI 2010, XXV Simposium Nacional de la Unión Científica Internacional de Radio, Bilbao
    Abstract:
    Plasmids are small chromosomes with the ability to pass from one cell to another. Recent advances in the study of its behavior shows that one of the main ways to assure its long-term survival is to adapt themselves to the cellular division mechanism of the host cell, assuring that at least one copy of the plasmid remains on each of the replicas generated in the cell-division process. Usually these studies have been made by hand by analyzing the images of a microscope and measuring the distance between each plasmid and the centre of the cell in which it is immersed. However, this manual process is slow and tedious, and reduces the applicability of the method to large image data sets. This communication shows an automated tool for cell segmentation based on a pre-emphasis filtering and parametric curve fitting that is able to accurately segment cells in microscopic images, count the plasmids inside it and extract its positions inside the cell.
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    • D02 Congresos [2]
    • D12 Congresos [523]

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    UNIVERSIDAD DE CANTABRIA

    Repositorio realizado por la Biblioteca Universitaria utilizando DSpace software
    Contact Us | Send Feedback
    Metadatos sujetos a:licencia de Creative Commons Reconocimiento 3.0 España