Show simple item record

dc.contributor.authorSalas García, Irene 
dc.contributor.authorFanjul Vélez, Félix 
dc.contributor.authorOrtega Quijano, Noé 
dc.contributor.authorArce Diego, José Luis 
dc.contributor.otherUniversidad de Cantabriaes_ES
dc.date.accessioned2013-07-15T15:09:44Z
dc.date.available2013-07-15T15:09:44Z
dc.date.issued2010-09
dc.identifier.urihttp://hdl.handle.net/10902/2648
dc.description.abstractPhotodynamic Therapy is a treatment modality based in biological material oxidation by using a photosensitizer and light. Treatment outcome with topical photosensitizers depends on the uneven distribution of drug through the tumour region and several studies have demonstrated the huge influence of corneal layer in the amount of photosensitizer accumulated in tumour tissue during the incubation period. In this work we present a PDT model for a topical photosensitizer that tries to predict the photodynamic effect on skin characterized by the permeability of the diffusion barrier layer exerted by the corneal layer. The results obtained allow us to estimate the citotoxicity reached in the treated area adjusting parameters related to the optical source, the photosensitizer concentration, the incubation and exposition time or the diffusivity and permeability of the damaged tissue.es_ES
dc.format.extent4 p.es_ES
dc.language.isospaes_ES
dc.rights© 2010 URSI Españaes_ES
dc.sourceURSI 2010, XXV Simposium Nacional de la Unión Científica Internacional de Radio, Bilbaoes_ES
dc.titleEfecto de la capa córnea en la respuesta fotodinámicaes_ES
dc.typeinfo:eu-repo/semantics/conferenceObjectes_ES
dc.rights.accessRightsopenAccesses_ES
dc.type.versionpublishedVersiones_ES


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record