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dc.contributor.authorGonzález López, Marcos Antonio 
dc.contributor.authorLacalle, Marina
dc.contributor.authorMata, Cristina
dc.contributor.authorLópez Escobar, María
dc.contributor.authorCorrales Martínez, Alfonso
dc.contributor.authorLópez Mejías, Raquel
dc.contributor.authorRueda Gotor, Javier
dc.contributor.authorGonzález Vela, María del Carmen 
dc.contributor.authorGonzález-Gay Mantecón, Miguel Ángel 
dc.contributor.authorBlanco Alonso, Ricardo
dc.contributor.authorHernández Hernández, José Luis 
dc.contributor.otherUniversidad de Cantabriaes_ES
dc.description.abstractINTRODUCTION: Hidradenitis suppurativa (HS) is a chronic inflammatory cutaneous disease which has been associated with an increased risk of adverse cardiovascular (CV) outcomes. Adequate stratification of the CV risk is an issue of major importance in patients with HS. To analyze the usefulness of carotid ultrasound (US) assessment for the CV disease risk stratification compared with a traditional score, the Framingham risk score (FRS), in a series of patients with HS. METHODS: Cross-sectional study of 60 patients with HS without history of CV events, diabetes mellitus or chronic kidney disease. Information on CV risk factors was collected and the FRS was calculated. Thus, the patients were classified into low, intermediate and high-CV disease risk categories based on FRS. Carotid US was performed in all participants, and the presence of atherosclerotic plaques was considered as a marker of high CV risk. RESULTS: HS patients had a mean age of 45.1±10.2 years, and 55% were female. The median FRS was 5.7 (IQR: 3.1-14.7). Twenty-four (40%) of the patients were classified into the low risk group, 28 (46.7%) in the intermediate risk group, and 8 (13.3%) into the FRS-high risk category. Noteworthy, carotid US revealed that about one-third of the patients (17/52; 32.6%) in the FRS-based low and intermediate risk categories had carotid plaques, and, therefore, they were reclassified into a high-risk category. CONCLUSION: CV risk in HS patients may be underestimated by using the FRS. Carotid US may be useful to improve the CV risk stratification of patients with HS.es_ES
dc.description.sponsorshipThis study was funded through an unrestricted grant provided by AbbVie to MGL. AbbVie has not played any role in study design, data collection and analysis, decision to publish or preparation of the manuscript.es_ES
dc.format.extent11 p.es_ES
dc.publisherPublic Library of Sciencees_ES
dc.rightsAttribution 4.0 Internationales_ES
dc.sourcePLoS One. 2018 Jan 4;13(1):e0190568es_ES
dc.titleCarotid ultrasound is useful for the cardiovascular risk stratification in patients with hidradenitis suppurativaes_ES
dc.relation.publisherVersion pone.0190568es_ES

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Attribution 4.0 InternationalExcept where otherwise noted, this item's license is described as Attribution 4.0 International