Low-density lipoprotein cholesterol and suicidal behaviour in a large sample of first-episode psychosis patients
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AuthorAyesa Arriola, Rosa; Canal Rivero, Manuel; Delgado Alvarado, Manuel; Setién Suero, María Esther; González Gómez, Jana; Labad, Javier; David, Anthony S.; Crespo Facorro, Benedicto
Objectives: Our aims were to confirm the relationship between lipid and lipoprotein concentrations and suicidal behaviour in first-episode psychosis (FEP) patients.
Methods: Suicidal behaviour was explored in a large FEP sample (N?=?383). Baseline lipid profile was compared between those who attempted or completed suicide and those who not presented suicidal behaviour.
Results: Low-density lipoprotein cholesterol (LDL-c) (OR?=?0.99, 95% CI=?0.98?1.00) and depressive symptoms (OR?=?1.15, 95% CI?=?1.06?1.24) were significantly related with suicidal behaviour.
Conclusions: Lipid profile test may be considered in the assessment of suicide risk in psychosis and LDL-c an important biological marker.
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