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dc.contributor.authorRodríguez Colmenares, Miguel Alejandro
dc.contributor.authorFanjul Vélez, Félix 
dc.contributor.authorArévalo Díaz, Laura
dc.contributor.authorArce Diego, José Luis 
dc.contributor.otherUniversidad de Cantabriaes_ES
dc.date.accessioned2018-04-11T08:50:59Z
dc.date.available2018-04-11T08:50:59Z
dc.date.issued2017
dc.identifier.isbn978-1-5106-0565-7
dc.identifier.isbn978-1-5106-0566-4
dc.identifier.issn0277-786X
dc.identifier.issn1996-756X
dc.identifier.otherMAT2015-69508-Pes_ES
dc.identifier.urihttp://hdl.handle.net/10902/13455
dc.description.abstractThe applications of nanoparticles in optical techniques of diagnosis and treatment of biological tissues are increasing. Image contrast can be improved in diagnostic approaches such as fluorescence, spectroscopy or optical coherence tomography. The therapeutic effect can be increased if nanoparticles are previously incorporated in the biological tissue. This is the case in thermotherapy, or in Photodynamic Therapy. All these applications take advantage of specific properties of the nanoparticles involved, either optical up- or down-conversion, thermal confinement or the ability to act as a drug-carrier. Although many biomedical applications that involve nanoparticles are being proposed and tested, there is a need to take into account the influence of those nanoparticles on optical radiation propagation. The previously mentioned optical treatment and diagnosis techniques assume a particular optical propagation pattern, which is altered by the addition of nanoparticles. This change depends on the nanoparticle material, shape, size and concentration, among other parameters. In order to try to quantify these changes, in this work several phantoms that include different nanoparticles are analyzed, in order to estimate the influence of nanoparticles in optical propagation. A theoretical model of optical propagation, which takes into account the absorption and scattering changes in the medium, is also considered. Nanoparticles of different sizes from 40 nm to 1µm are analyzed. Nanoparticle materials of interest in biomedical applications are employed. The results are relevant in diagnosis interpretation of images and treatment outcome evaluation when nanoparticles are present.es_ES
dc.description.sponsorshipThis work has been partially supported by the project “New active phases in transition metals and rare earth nano-oxides stabilized at high pressure” (MAT2015-69508-P) of the Spanish Ministry of Economy and Competitiveness, cofunded by FEDER funds, and by the San Cándido Foundation.es_ES
dc.format.extent5 p.es_ES
dc.language.isoenges_ES
dc.publisherSPIE Society of Photo-Optical Instrumentation Engineerses_ES
dc.rightsCopyright 2017 Society of Photo-Optical Instrumentation Engineers and Optical Society of America. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.es_ES
dc.sourceProceedings of SPIE, 2017, 10062, 100620Wes_ES
dc.sourceOptical Interactions with Tissue and Cells XXVIII, San Francisco, 2017es_ES
dc.subject.otherNanoparticleses_ES
dc.subject.otherTissue simulating phantomses_ES
dc.subject.otherOptical propagationes_ES
dc.subject.otherOptical propertieses_ES
dc.titleAnalysis of nanoparticles optical propagation influence in biological tissue simulating phantomses_ES
dc.typeinfo:eu-repo/semantics/conferenceObjectes_ES
dc.relation.publisherVersionhttps://doi.org/10.1117/12.2252452es_ES
dc.rights.accessRightsopenAccesses_ES
dc.identifier.DOI10.1117/12.2252452
dc.type.versionpublishedVersiones_ES


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