dc.contributor.author | Cayô da Silva, Rodrigo | |
dc.contributor.author | Merino Carballeira, María | |
dc.contributor.author | Ruiz del Castillo, Belén | |
dc.contributor.author | Cano García, María Eliecer | |
dc.contributor.author | Calvo Montes, Jorge | |
dc.contributor.author | Bou Arévalo, Germán | |
dc.contributor.author | Martínez Martínez, Luis | |
dc.contributor.other | Universidad de Cantabria | es_ES |
dc.date.accessioned | 2015-10-06T07:48:24Z | |
dc.date.available | 2015-10-06T07:48:24Z | |
dc.date.issued | 2014-08 | |
dc.identifier.issn | 0066-4804 | |
dc.identifier.uri | http://hdl.handle.net/10902/7262 | |
dc.description.abstract | A carbapenem-resistant Acinetobacter pittii strain carrying an OXA-24-like enzyme was isolated in northern Spain in 2008. Sequence analysis confirmed the presence of the novel bla(OXA-207) gene flanked by the site-specific XerC/XerD-like recombination binding sites and showing a unique Gly222Val substitution compared to OXA-24. Cloning and kinetic analysis showed that OXA-207 presents a reduction in the catalytic efficiency against carbapenems and a noticeable increase for oxacillin. | es_ES |
dc.format.extent | 5 p. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | American Society for Microbiology | es_ES |
dc.rights | © American Society for Microbiology | es_ES |
dc.source | Antimicrobial Agents and Chemotherapy. 2014 Aug;58(8):4944-8 | es_ES |
dc.title | OXA-207, a novel OXA-24 variant with reduced catalytic efficiency against carbapenems in Acinetobacter pittii from Spain | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.rights.accessRights | openAccess | es_ES |
dc.identifier.DOI | 10.1128/AAC.02633-13 | |
dc.type.version | publishedVersion | es_ES |