| dc.contributor.author | Pelayo Terán, José María | es_ES |
| dc.contributor.author | Pérez Iglesias, Rocio | es_ES |
| dc.contributor.author | Vázquez Bourgon, Javier | es_ES |
| dc.contributor.author | Mata Pastor, Ignacio | es_ES |
| dc.contributor.author | Carrasco Marín, Eugenio | es_ES |
| dc.contributor.author | Vázquez Barquero, José Luis | es_ES |
| dc.contributor.author | Crespo Facorro, Benedicto | es_ES |
| dc.contributor.other | Universidad de Cantabria | es_ES |
| dc.date.accessioned | 2026-01-27T11:34:51Z | |
| dc.date.available | 2026-01-27T11:34:51Z | |
| dc.date.issued | 2011-01-30 | es_ES |
| dc.identifier.issn | 0165-1781 | es_ES |
| dc.identifier.issn | 1872-7123 | es_ES |
| dc.identifier.uri | https://hdl.handle.net/10902/38908 | |
| dc.description.abstract | Genetic factors play an important role in the understanding of clinical response to antipsychotic treatments. We aimed to assess the effect of the catechol-O-methyltransferase (COMT) genotype in the short-term (6 weeks) clinical response of 161 first-episode psychosis patients. COMT genotype was not related to clinical response at 6 weeks. Val homozygote patients showed higher negative symptoms than Met homozygote patients. The COMT Val158 genotype seems to be related to the severity of negative symptoms rather than to clinical response. | es_ES |
| dc.format.extent | 4 p. | es_ES |
| dc.language.iso | eng | es_ES |
| dc.publisher | Elsevier | es_ES |
| dc.rights | Alojado según Resolución CNEAI 10/12/25 (ANECA) © 2010 Elsevier Ireland Ltd. All rights reserved. | es_ES |
| dc.source | Psychiatry Research, 2011, 185(1-2), 286-289 | es_ES |
| dc.subject.other | COMT Val158Met | es_ES |
| dc.subject.other | Antipsychotic response | es_ES |
| dc.subject.other | First episode psychosis | es_ES |
| dc.subject.other | Psychosis | es_ES |
| dc.subject.other | Neuroimaging-genetics | es_ES |
| dc.title | Catechol-O-methyltransferase Val158Met polymorphism and negative symptoms after acute antipsychotic treatment in first-episode non-affective psychosis | es_ES |
| dc.type | info:eu-repo/semantics/article | es_ES |
| dc.relation.publisherVersion | https://doi.org/10.1016/j.psychres.2010.06.006 | es_ES |
| dc.rights.accessRights | closedAccess | es_ES |
| dc.identifier.DOI | 10.1016/j.psychres.2010.06.006 | es_ES |
| dc.type.version | publishedVersion | es_ES |
