dc.contributor.author | Gutiérrez Villanueva, Andrea | |
dc.contributor.author | Muñoz, Patricia | |
dc.contributor.author | Delgado Montero, Antonia | |
dc.contributor.author | Olmedo Samperio, Maria | |
dc.contributor.author | Alarcón González, Arístides de | |
dc.contributor.author | Gutiérrez Carretero, Encarnación | |
dc.contributor.author | Zarauza Navarro, Manuel Jesús | |
dc.contributor.author | García i Pares, Delia | |
dc.contributor.author | Goenaga, Miguel Ángel | |
dc.contributor.author | Ojeda Burgos, Guillermo | |
dc.contributor.author | Goikoetxea Agirre, Ane Josune | |
dc.contributor.author | Reguera Iglesias, José Mª | |
dc.contributor.author | Ramos, Antonio | |
dc.contributor.author | Fernández Cruz, Ana | |
dc.contributor.author | Fariñas Álvarez, María del Carmen | |
dc.contributor.other | Universidad de Cantabria | es_ES |
dc.date.accessioned | 2022-03-31T16:27:33Z | |
dc.date.available | 2022-03-31T16:27:33Z | |
dc.date.issued | 2021-07-26 | |
dc.identifier.issn | 2193-8229 | |
dc.identifier.issn | 2193-6382 | |
dc.identifier.uri | http://hdl.handle.net/10902/24468 | |
dc.description.abstract | Introduction: Mural infective endocarditis (MIE) is a rare type of endovascular infection. We present a comprehensive series of patients with mural endocarditis. Methods: Patients with infectious endocarditis (IE) from 35 Spanish hospitals were prospectively included in the GAMES registry between 2008 and 2017. MIEs were compared to non-MIEs. We also performed a literature search for cases of MIE published between 1979 and 2019 and compared them to the GAMEs series. Results: Twenty-seven MIEs out of 3676 IEs were included. When compared to valvular IE (VIE) or device-associated IE (DIE), patients with MIE were younger (median age 59 years, p \0.01). Transplantation (18.5% versus 1.6% VIE and 2% DIE, p \ 0.01), hemodialysis (18.5% versus 4.3% VIE and 4.4% DIE, p = 0.006), catheter source (59.3% versus 9.7% VIE and 8.8% DIE, p \ 0.01) and Candida etiology (22.2% versus 2% DIE and 1.2% VIE, p \ 0.01) were more common in MIE, whereas the Charlson Index was lower (4 versus 5 in non MIE, p = 0.006). Mortality was similar.MIE from the literature shared many characteristics with MIE from GAMES, although patients were younger (45 years vs. 56 years, p \ 0.001), the Charlson Index was lower (1.3 vs. 4.3, p = 0.0001), catheter source was less common (13.9% vs. 59.3%) and there were more IVDUs (25% vs. 3.7%). S. aureus was the most frequent microorganism (50%, p = 0.035). Systemic complications were more common but mortality was similar. Conclusion: MIE is a rare entity. It is often a complication of catheter use, particularly in immunocompromised and hemodialysis patients. Fungal etiology is common. Mortality is similar to other IEs. | es_ES |
dc.format.extent | 16 p. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Springer Nature | es_ES |
dc.rights | ©Los autores | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by-nc/4.0/ | * |
dc.source | Infectious Diseases and Therapy (2021) 10:2749?2764 | es_ES |
dc.subject.other | Endocarditis | es_ES |
dc.subject.other | Mural | es_ES |
dc.subject.other | Non-valvular endocarditis | es_ES |
dc.title | Mural Endocarditis: The GAMES Registry Series and Review of the Literature | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.relation.publisherVersion | https://doi.org/10.1007/s40121-021-00490-y | es_ES |
dc.rights.accessRights | openAccess | es_ES |
dc.identifier.DOI | doi.org/10.1007/s40121-021-00490-y | |
dc.type.version | publishedVersion | es_ES |