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dc.contributor.authorGutiérrez Villanueva, Andrea
dc.contributor.authorMuñoz, Patricia
dc.contributor.authorDelgado Montero, Antonia
dc.contributor.authorOlmedo Samperio, Maria
dc.contributor.authorAlarcón González, Arístides de
dc.contributor.authorGutiérrez Carretero, Encarnación
dc.contributor.authorZarauza Navarro, Manuel Jesús 
dc.contributor.authorGarcía i Pares, Delia
dc.contributor.authorGoenaga, Miguel Ángel
dc.contributor.authorOjeda Burgos, Guillermo
dc.contributor.authorGoikoetxea Agirre, Ane Josune
dc.contributor.authorReguera Iglesias, José Mª
dc.contributor.authorRamos, Antonio
dc.contributor.authorFernández Cruz, Ana
dc.contributor.authorFariñas Álvarez, María del Carmen 
dc.contributor.otherUniversidad de Cantabriaes_ES
dc.date.accessioned2022-03-31T16:27:33Z
dc.date.available2022-03-31T16:27:33Z
dc.date.issued2021-07-26
dc.identifier.issn2193-8229
dc.identifier.issn2193-6382
dc.identifier.urihttp://hdl.handle.net/10902/24468
dc.description.abstractIntroduction: Mural infective endocarditis (MIE) is a rare type of endovascular infection. We present a comprehensive series of patients with mural endocarditis. Methods: Patients with infectious endocarditis (IE) from 35 Spanish hospitals were prospectively included in the GAMES registry between 2008 and 2017. MIEs were compared to non-MIEs. We also performed a literature search for cases of MIE published between 1979 and 2019 and compared them to the GAMEs series. Results: Twenty-seven MIEs out of 3676 IEs were included. When compared to valvular IE (VIE) or device-associated IE (DIE), patients with MIE were younger (median age 59 years, p \0.01). Transplantation (18.5% versus 1.6% VIE and 2% DIE, p \ 0.01), hemodialysis (18.5% versus 4.3% VIE and 4.4% DIE, p = 0.006), catheter source (59.3% versus 9.7% VIE and 8.8% DIE, p \ 0.01) and Candida etiology (22.2% versus 2% DIE and 1.2% VIE, p \ 0.01) were more common in MIE, whereas the Charlson Index was lower (4 versus 5 in non MIE, p = 0.006). Mortality was similar.MIE from the literature shared many characteristics with MIE from GAMES, although patients were younger (45 years vs. 56 years, p \ 0.001), the Charlson Index was lower (1.3 vs. 4.3, p = 0.0001), catheter source was less common (13.9% vs. 59.3%) and there were more IVDUs (25% vs. 3.7%). S. aureus was the most frequent microorganism (50%, p = 0.035). Systemic complications were more common but mortality was similar. Conclusion: MIE is a rare entity. It is often a complication of catheter use, particularly in immunocompromised and hemodialysis patients. Fungal etiology is common. Mortality is similar to other IEs.es_ES
dc.format.extent16 p.es_ES
dc.language.isoenges_ES
dc.publisherSpringer Naturees_ES
dc.rights©Los autoreses_ES
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/*
dc.sourceInfectious Diseases and Therapy (2021) 10:2749?2764es_ES
dc.subject.otherEndocarditises_ES
dc.subject.otherMurales_ES
dc.subject.otherNon-valvular endocarditises_ES
dc.titleMural Endocarditis: The GAMES Registry Series and Review of the Literaturees_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.relation.publisherVersionhttps://doi.org/10.1007/s40121-021-00490-yes_ES
dc.rights.accessRightsopenAccesses_ES
dc.identifier.DOIdoi.org/10.1007/s40121-021-00490-y
dc.type.versionpublishedVersiones_ES


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