Estudio de asociación del déficit cognitivo y la función respiratoria en pacientes con psicosis

Abstract

Introduction: Psychotic disorders are associated with a higher prevalence of risky behaviours such as tobacco or cannabis use. These patients have poorer levels of respiratory and cognitive function than healthy patients. Objective: Patients with impaired cognitive function will present higher levels of respiratory deficit than patients with psychosis without cognitive complaint. Methodology: The present study was carried out as part of a longitudinal study in first episodes of non-affective psychosis (PAFIP), at the Marqués de Valdecilla University Hospital (HUMV), in Cantabria. 203 subjects were evaluated (128 patients with psychosis and 75 control subjects). The study included clinical, physical and sociodemographic variables, a cognitive and respiratory evaluation and an evaluation of quality of life. Results: Subjects with cognitive deficit present a lower maximum capacity for exhaled air volume (FVC), a greater risk of presenting low DCLO (diffusing capacity for carbon monoxide), some differences in the dyspnea subscales, and worse quality of life results. Patients with cognitive deficit use to present a greater rate of tobacco and cannabis use. Conclusions: Despite methodological limitations, such as the small sample size or the low presence of COPD in the patients, some conclusions were drawn. Subjects with cognitive deficit present a poorer respiratory health than those without cognitive deficit. The consumption of tobacco and cannabis are not entirely significant in this study.