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Standardization procedure for flow cytometry data harmonization in prospective multicenter studies

dc.contributor.authorLucas Le Lann
dc.contributor.authorPierre-Emmanuel Jouve
dc.contributor.authorMarta Alarcón-Riquelme
dc.contributor.authorChristophe Jamin
dc.contributor.authorJacques-Olivier Pers
dc.contributor.authorBlanco Alonso, Ricardo 
dc.contributor.authorGonzález-Gay Mantecón, Miguel Ángel 
dc.contributor.otherUniversidad de Cantabriaes_ES
dc.date.accessioned2021-04-14T11:34:04Z
dc.date.available2021-04-14T11:34:04Z
dc.date.issued2020
dc.identifier.issn2045-2322
dc.identifier.urihttp://hdl.handle.net/10902/21203
dc.description.abstractOne of the most challenging objective for clinical cytometry in prospective multicenter immunomonitoring trials is to compare frequencies, absolute numbers of leukocyte populations and further the mean fluorescence intensities of cell markers, especially when the data are generated from different instruments. Here, we describe an innovative standardization workflow to compare all data to carry out any large-scale, prospective multicentric flow cytometry analysis whatever the duration, the number or type of instruments required for the realization of such projectses_ES
dc.format.extent8 p.es_ES
dc.language.isoenges_ES
dc.publisherNature Publishing Groupes_ES
dc.rightsAttribution 4.0 International © The Author(s)es_ES
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.sourceScientific Reports 10, 11567 (2020).es_ES
dc.titleStandardization procedure for flow cytometry data harmonization in prospective multicenter studieses_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.relation.publisherVersionhttps://doi.org/10.1038/s41598-020-68468-3es_ES
dc.rights.accessRightsopenAccesses_ES
dc.identifier.DOI10.1038/s41598-020-68468-3
dc.type.versionpublishedVersiones_ES


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