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dc.contributor.authorSana, Alibi
dc.contributor.authorCrespo Santiago, Dámaso 
dc.contributor.authorNavas Méndez, Jesús 
dc.contributor.otherUniversidad de Cantabriaes_ES
dc.date.accessioned2021-02-26T10:29:10Z
dc.date.available2021-02-26T10:29:10Z
dc.date.issued2021
dc.identifier.issn2079-6382
dc.identifier.urihttp://hdl.handle.net/10902/20816
dc.description.abstractThe vegetal world constitutes the main factory of chemical products, in particular secondary metabolites like phenols, phenolic acids, terpenoids, and alkaloids. Many of these compounds are small molecules with antibacterial activity, although very few are actually in the market as antibiotics for clinical practice or as food preservers. The path from the detection of antibacterial activity in a plant extract to the practical application of the active(s) compound(s) is long, and goes through their identification, purification, in vitro and in vivo analysis of their biological and pharmacological properties, and validation in clinical trials. This review presents an update of the main contributions published on the subject, focusing on the compounds that showed activity against multidrug-resistant relevant bacterial human pathogens, paying attention to their mechanisms of action and synergism with classical antibiotics.es_ES
dc.format.extent19 p.es_ES
dc.language.isoenges_ES
dc.publisherMDPIes_ES
dc.rightsAttribution 4.0 Internationales_ES
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.sourceAntibiotics 2021, 10(3), 231es_ES
dc.subject.otherPlant‐derivateses_ES
dc.subject.otherAntibacterial activityes_ES
dc.subject.otherMulti‐drug resistancees_ES
dc.subject.otherSmall moleculeses_ES
dc.titlePlant-Derivatives Small Molecules with Antibacterial Activityes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.relation.publisherVersionhttps://doi.org/10.3390/antibiotics10030231es_ES
dc.rights.accessRightsopenAccesses_ES
dc.identifier.DOI10.3390/antibiotics10030231
dc.type.versionpublishedVersiones_ES


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Attribution 4.0 InternationalExcepto si se señala otra cosa, la licencia del ítem se describe como Attribution 4.0 International