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CD133-directed CAR T-cells for MLL Leukemia: On-Target, Off-Tumor Myeloablative Toxicity

dc.contributor.authorBueno, Clara
dc.contributor.authorVelasco-Hernandez, Talia
dc.contributor.authorGutiérrez-Agüera, Francisco
dc.contributor.authorZanetti, Samanta Romina
dc.contributor.authorBaroni, Matteo L.
dc.contributor.authorSánchez-Martínez, Diego
dc.contributor.authorMolina, Oscar
dc.contributor.authorClosa, Adria
dc.contributor.authorAgraz Doblas, Antonio Manuel
dc.contributor.authorMarín, Pedro
dc.contributor.authorEyras, Eduardo
dc.contributor.authorVarela Egocheaga, Ignacio 
dc.contributor.authorMenéndez, Pablo
dc.contributor.otherUniversidad de Cantabriaes_ES
dc.date.accessioned2020-02-07T16:29:03Z
dc.date.available2020-02-07T16:29:03Z
dc.date.issued2019
dc.identifier.issn0887-6924
dc.identifier.issn1476-5551
dc.identifier.otherSAF-SAF2016-80481-Res_ES
dc.identifier.otherBIO2017-85364-Res_ES
dc.identifier.urihttp://hdl.handle.net/10902/18113
dc.description.sponsorshipAcknowledgements: We thank the Interfant treatment protocol and local physicians for contributing patient samples: Dr. Ronald W Stam (Princess Maxima Centre, Utrech), Dr. Mireia Camos and Dr. Jose Luis Fuster (Spanish Society of Pediatric Hematoncology), Dr. Paola Ballerini (A. Trousseau Hospital, Paris). We also thank Prof. Paresh Vyas (Oxford Univeristy, UK) and Prof. Kajsa Paulsson (Lund University, Sweden) for facilitating access to their RNA-seq database. This work has been supported by the European Research Council (CoG-2014-646903, PoC-2018-811220) to PM, the Spanish Ministry of Economy and Competitiveness (MINECO, SAF-SAF2016-80481-R, BIO2017-85364-R) to PM and EE, the Generalitat de Catalunya (SGR330, SGR102 and PERIS) to PM and EE, the Spanish Association against cancer (AECC-CI-2015) to CB, and the Health Institute Carlos III (ISCIII/FEDER, PI14-01191) to CB. PM also acknowledges financial support from the Obra Social La Caixa-Fundaciò Josep Carreras. SRZ and TV are supported by a Marie Curie fellowships. OM is supported by the Catalan Government through a Beatriu de Pinos fellowship. MB is supported by MINECO through a PhD scholarship. PM is an investigator of the Spanish Cell Therapy cooperative network (TERCEL).es_ES
dc.format.extent4 p.es_ES
dc.language.isoenges_ES
dc.publisherNature Publishing Groupes_ES
dc.rightsAttribution 4.0 Internationales_ES
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.sourceLeukemia, 33 (8), 2090-2125 Aug 2019es_ES
dc.titleCD133-directed CAR T-cells for MLL Leukemia: On-Target, Off-Tumor Myeloablative Toxicityes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.relation.publisherVersionhttps://doi.org/10.1038/s41375-019-0418-8es_ES
dc.rights.accessRightsopenAccesses_ES
dc.identifier.DOI10.1038/s41375-019-0418-8
dc.type.versionpublishedVersiones_ES


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