Low-density lipoprotein cholesterol and suicidal behaviour in a large sample of first-episode psychosis patients

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URI: http://hdl.handle.net/10902/15309
ISSN: 1562-2975
ISSN: 1814-1412
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Autoría
Ayesa Arriola, RosaAutoridad Unican; Canal Rivero, Manuel; Delgado Alvarado, Manuel; Setién Suero, María Esther; González Gómez, Jana; Labad, Javier; David, Anthony S.; Crespo Facorro, BenedictoAutoridad Unican
Fecha
2018-12
Derechos
©Taylor and Francis. This is an Accepted Manuscript of an article published by Taylor & Francis in The World Journal of Biological Psychiatry on December 2018, available online: http://www.tandfonline.com/10.1080/15622975.2017.1414305
Publicado en
The World Journal of Biological Psychiatry Volume 19, 2018 - Issue sup3: Pages S158-S161
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Taylor & Francis
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Palabras clave
Cholesterol
First Episode Psychosis
Lipoproteins
Schizophrenia
Suicide
Resumen/Abstract
Objectives: Our aims were to confirm the relationship between lipid and lipoprotein concentrations and suicidal behaviour in first-episode psychosis (FEP) patients. Methods: Suicidal behaviour was explored in a large FEP sample (N?=?383). Baseline lipid profile was compared between those who attempted or completed suicide and those who not presented suicidal behaviour. Results: Low-density lipoprotein cholesterol (LDL-c) (OR?=?0.99, 95% CI=?0.98?1.00) and depressive symptoms (OR?=?1.15, 95% CI?=?1.06?1.24) were significantly related with suicidal behaviour. Conclusions: Lipid profile test may be considered in the assessment of suicide risk in psychosis and LDL-c an important biological marker.
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