@article{10902/6223, year = {2010}, month = {9}, url = {http://hdl.handle.net/10902/6223}, abstract = {Objective: To evaluate the time course of bone mineral density (BMD) in women with anorexia nervosa (AN) during two years of follow-up. Methods: We prospectively studied 51 female with AN aged 18-38 years, and forty age-matched healthy women (19-34 years). BMD was measured in lumbar spine (LS), femoral neck (FN) and total hip (TH) by DXA. Results: At baseline, weight, body mass index, and lumbar and hip BMD were significantly (p<0.001) lower in AN patients than in controls. Patients who gain weight showed a significant increase in BMD at FN (+1.6%; p<0.05), and TH (+4.4%; p<0.05) and lower non significant changes in LS (+1.3%). Weight at entry, and percent change of weight were significant determinants (p<0.05) of the variability in percent change of BMD at FN and TH, whereas weight at entry was the main determinant of bone modifications at lumbar spine. Conclusions: Our data emphasize the influence of weight gain in recovery of bone mass in AN patients, especially at the hip.}, publisher = {Wiley}, publisher = {International Journal of Eating Disorders. 2010 Sep;43(6):537-42}, title = {Time course of bone loss in patients with anorexia nervosa}, author = {Olmos Martínez, José Manuel and Valero Díaz de Lamadrid, Carmen and Gómez del Barrio, José Andrés and Amado Señarís, José Antonio and Hernández Hernández, José Luis and Menéndez Arango, José and González Macías, Jesús}, }