@article{10902/539,
year = {2008},
month = {6},
url = {http://hdl.handle.net/10902/539},
abstract = {Introduction
A large part of research into drug addiction focuses on mesolimbic dopamine circuitry; however, both alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and/or kainate and dopamine D2 receptors can play a role in maintaining the established addiction. 

Case presentation
We report the case of a 34-year-old man who compulsively smoked 80 to 100 cigarettes each day. After receiving treatment with topiramate and aripiprazole, his tobacco consumption was dramatically reduced. 

Conclusion
Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and/or kainate blocking agents and a dopamine D2 receptor partial agonist may be novel instruments for nicotine abuse disorders},
publisher = {BioMed Central},
publisher = {Journal of Medical Case Reports, 2008, 2:198},
title = {Decrease in tobacco consumption after treatment with topiramate and aripiprazole: a case report},
author = {Arbaizar, Beatriz and Gómez Acebo, Inés and Llorca Díaz, Javier},
}