@article{10902/4584, year = {2014}, month = {4}, url = {http://hdl.handle.net/10902/4584}, abstract = {Photodynamic therapy (PDT) dosimetric tools are crucial for treatment planning and noninvasive monitoring by means of fluorescence. Present approaches consider usually a 1D problem, a simple photochemical process, or a spatially homogeneous photosensitizer. In this work, a radially resolved superficial photosensitizer fluorescence and 3D photochemical time-dependent PDT model are presented. The model provides a time-dependent estimation of tissue fluorescence and the photosensitizer and singlet oxygen 3D concentrations. The model is applied to a basal cell carcinoma treated by Metvix topical photosensitizer protocol. The analysis shows the potentiality in treatment planning and monitoring. The fluorescence results are in agreement with previous measurements.}, publisher = {The Optical Society (OSA)}, publisher = {Optics Letters, 2014, 39(7), 1845-1848}, title = {Superficial radially resolved fluorescence and 3D photochemical time-dependent model for photodynamic therapy}, author = {Salas García, Irene and Fanjul Vélez, Félix and Arce Diego, José Luis}, }