@article{10902/38908,
year = {2011},
month = {1},
url = {https://hdl.handle.net/10902/38908},
abstract = {Genetic factors play an important role in the understanding of clinical response to antipsychotic treatments. We aimed to assess the effect of the catechol-O-methyltransferase (COMT) genotype in the short-term (6 weeks) clinical response of 161 first-episode psychosis patients. COMT genotype was not related to clinical response at 6 weeks. Val homozygote patients showed higher negative symptoms than Met homozygote patients. The COMT Val158 genotype seems to be related to the severity of negative symptoms rather than to clinical response.},
publisher = {Elsevier},
publisher = {Psychiatry Research, 2011, 185(1-2), 286-289},
title = {Catechol-O-methyltransferase Val158Met polymorphism and negative symptoms after acute antipsychotic treatment in first-episode non-affective psychosis},
author = {Pelayo Terán, José María and Pérez Iglesias, Rocio and Vázquez Bourgon, Javier and Mata Pastor, Ignacio and Carrasco Marín, Eugenio and Vázquez Barquero, José Luis and Crespo Facorro, Benedicto},
}