@article{10902/37451, year = {2025}, url = {https://hdl.handle.net/10902/37451}, abstract = {We created and validated the Neuro-Score, a specific scale to detect and monitor cognitive impairment, including mild stages, in kidney or liver transplant recipients. A qualitative study was conducted to define a preliminary set of 62 items. Item reduction was performed using exploratory factor analysis. Confirmatory factor analysis assessed the adequacy of the factorial solution. The total scores of the Neuro-Score and mini-mental state examination were compared. Responsiveness to change was evaluated from visit 1 (baseline) to 2A (18 months later) and temporal stability from visit 2A to 2B (1-2 weeks later). Factor analysis showed 11 factors with an eigenvalue of >1. Confirmatory factor analysis yielded a logical solution with 1 factor and 11 items that explained 27.9% of the variance. The final model showed satisfactory internal consistency (Cronbach ? = 0.82). A weak negative correlation was found between Neuro-Score and mini-mental state examination total scores (Pearson r = ?0.12; P = .0095). The Neuro-Score responsiveness to change was demonstrated (P = .022). No significant differences in the total score were observed between visits 2A and 2B, supporting the Neuro-Score temporal stability. The Neuro-Score scale is a simple, reliable, self-administered, easy-to-interpret, and consistent 11-item scale to detect and monitor cognitive impairment in kidney and liver transplant recipients.}, publisher = {Elsevier}, publisher = {American Journal of Transplantation, 2025, 25(5),1059-1069}, title = {Development and validation of the Neuro-Score: a specific scale to detect and monitor cognitive impairment in kidney or liver transplant recipients}, author = {Moreso, Francesc and Pons Miñano, José Antonio and Sánchez Fructuoso, Ana and Jacas, Carlos and Alegret, Montserrat and Ferrer, Montserrat and Colmenero, Jordi and Andrés Belmonte, Amado and López Jiménez, Verónica and Pascual, Sonia and Mazuecos Blanca, Auxiliadora and Ventura Galiano, Ana Paz and Cachero, Alba and Rivero, Antonio and Crespo, Marta and Cuadrado Lavín, Antonio and Caballero Marcos, Arantxa and Gonzalez Diéguez, Maria Luisa and Almohalla Alvarez, Carolina and Maruri Kareaga, Naroa}, }