@article{10902/36641,
year = {2025},
month = {4},
url = {https://hdl.handle.net/10902/36641},
abstract = {Multiple myeloma (MM) diagnosis requires 10% plasma cell (PC) infiltration in the bone marrow (BM), detected by bone marrow aspiration (BMA) or biopsy (BMB). We evaluated the concordance of these 2 techniques in 189 patients. In 43 cases (23%), the techniques were discordant, 10 due to poor sample quality. In the remaining 33 patients, BMB diagnosed MM, while BMA detected < 10% PC, being symptomatic in 16 patients and smouldering (SMM) in 17. Without an initial BMB, 11% would have been misdiagnosed; and 12% of symptomatic patients would require a second BMA or BMB for strict diagnosis according to current criteria.},
publisher = {Elsevier},
publisher = {Clinical Lymphoma, Myeloma & Leukemia, 2025, 25(4), e210-e213},
title = {Is bone marrow trephine biopsy necessary in multiple myeloma patients at diagnosis?},
author = {Gea, Ana and Fernández, Tatiana and Fernández Luis, Sara and Domínguez García, Juan José and Francés, Irene and Tobalina, Ana and Cantera, Rodrigo and Bannatyne, Julia and Gorostidi, Irene and Oviedo, María and Cerezo, Juan M. and García, Raquel and Insunza Gaminde, Andrés and Montes Gaisán, Carmen María and Bermúdez, Aránzazu and Montes Moreno, Santiago and Briz, Montserrat and Ocio San Miguel, Enrique María},
}