@article{10902/36396,
year = {2024},
url = {https://hdl.handle.net/10902/36396},
abstract = {Traumatic brain injury (TBI) is a leading cause of disability and mortality globally, stemming from both primary mechanical injuries and subsequent secondary responses. Effective early management of moderate-to-severe TBI is essential to prevent secondary damage and improve patient outcomes. This review provides a comprehensive guide for the resuscitation and stabilization of TBI patients, combining clinical experience with current evidence-based guidelines. Key areas addressed in this study include the identification and classification of severe TBI, intubation strategies, and optimized resuscitation targets to maintain cerebral perfusion. The management of coagulopathy and special considerations for patients with concomitant hemorrhagic shock are discussed in depth, along with recommendations for neurosurgical interventions. This article further explores the role of multimodal neuromonitoring and targeted temperature management to mitigate secondary brain injury. Finally, it discusses end-of-life care in cases of devastating brain injury (DBI). This practical review integrates foundational and recent advances in TBI management to aid in reducing secondary injuries and enhancing long-term recovery, presenting a multidisciplinary approach to support acute care decisions in TBI patients.},
organization = {Funding: This research received no external funding.},
publisher = {MDPI},
publisher = {Journal of Clinical Medicine, 2024, 13(23), 7325},
title = {Resuscitation and initial management after moderate-to-severe traumatic brain injury: questions for the on-call shift},
author = {Barea-Mendoza, Jesús Abelardo and Chico-Fernández, Mario and Ballesteros Sanz, María Ángeles and Caballo Manuel, Alejandro and Castaño-León, Ana M. and Egea-Guerrero, J. J. and Lagares, Alfonso and Morales-Varas, Guillermo and Pérez-Bárcena, Jon and Serviá Goixart, Luis and Llompart-Pou, Juan Antonio},
}