@article{10902/36184,
year = {2020},
month = {9},
url = {https://hdl.handle.net/10902/36184},
abstract = {The study of gender differences may lead into improvement in patient care. We have aimed to identify the gender differences in heart transplantation (HT) of adult HT recipients in Spain and their evolution in a study covering the years 1993-2017 in which 6740 HT (20.6% in women) were performed. HT indication rate per million inhabitants was lower in women, remaining basically unchanged during the 25-year study period. HT rate was higher in men, although this decreased over the 25-year study period. Type of heart disease differed in men versus women (p < .001): ischemic heart disease 47.6% versus 22.5%, dilated cardiomyopathy 41.3% versus 34.6%, or other 36% versus 17.8%, respectively. Men were more frequently diabetics (18% vs. 13.1% p < .001), hypertensives (33.1% vs. 24% p < .001), and smokers (21.7% vs. 12.9% p < .001), respectively. Women had more pre-HT malignancies (7.1% vs. 2.8% p < .001), and their clinical status was worse at HT due to renal function and mechanical ventilation. Adjusted survival (p = .198) and most of the mortality-related variables were similar in men and women. Death occurred more frequently in women due to rejection (7.9% vs. 5.1% p < .001) and primary failure (18.2% vs. 12.5% p < .001) and in men due to malignancies (15.1% vs. 6.6% p < .001).},
organization = {Funding information: This investigation was funded by the Centro de Investigación en Red de Enfermedades Cardiovasculares (CIBERCV), Instituto de Salud Carlos III, Spanish Ministry of Economy and Competitiveness. Acknowledgments: We thank Javier Muñiz for his statistical assistance and Barbara Shapiro for her excellent work of translation and English revision of the paper.},
publisher = {Wiley},
publisher = {Clinical Transplantation, 2020, 34, e14096},
title = {Gender differences in heart transplantation: twenty-five year trends in the nationwide Spanish heart transplant registry},
author = {García Cosio, María D. and González Vílchez, Francisco Jesús and López Vilella, Raquel and Barge Caballero, Eduardo and Gómez Buen, Manuel and Martínez Selles, Manuel and Arizón, Jose M. and Rangel Sousa, Diego and González Costello, José and Mirabet, Sonia and Pérez Villa, Félix and Díaz Molina, Beatriz and Rábago, Gregorio and Portolés Ocampo, Ana and Fuente Galán, Luis de la and Garrido, Iris and Delgado Jiménez, Juan F.},
}