@article{10902/35169,
year = {2021},
url = {https://hdl.handle.net/10902/35169},
abstract = {Aims: To study whether the consumption of ultra-processed foods and drinks is associated with breast, colorectal, and prostate cancers.
Methods: Multicentric population-based case-control study (MCC-Spain) conducted in 12 Spanish provinces. Participants were men and women between 20 and 85 years of age with diagnoses of colorectal (n = 1852), breast (n = 1486), or prostate cancer (n = 953), and population-based controls (n = 3543) frequency-matched by age, sex, and region. Dietary intake was collected using a validated food frequency questionnaire. Foods and drinks were categorized according to their degree of processing based on the NOVA classification. Unconditional multivariable logistic regression was used to evaluate the association between ultra-processed food and drink consumption and colorectal, breast, and prostate cancer.
Results: In multiple adjusted models, consumption of ultra-processed foods and drinks was associated with a higher risk of colorectal cancer (OR for a 10% increase in consumption: 1.11; 95% CI 1.04-1.18). The corresponding odds for breast (OR 1.03; 95% CI 0.96-1.11) and prostate cancer (OR 1.02; 95% CI 0.93-1.12) were indicative of no association.
Conclusions: Results of this large population-based case-control study suggest an association between the consumption of ultra-processed foods and drinks and colorectal cancer. Food policy and public health should include a focus on food processing when formulating dietary guidelines.
Keywords: Breast cancer; Case-control study; Colorectal cancer; Prostate cancer; Ultra-processed foods and drinks.},
organization = {This research was partially funded by public grants from the Catalan Government (2014SGR756, 2017SGR1085, 2017SGR733, SLT006/17/76), and European Regional Development Fund-ERDF, by the “Acción Transversal del Cancer”, approved by the Spanish Ministry Council on 11 October 2007, by the Instituto de Salud Carlos III-FEDER (PI08/1770, PI08/0533, PI08/1359, PS09/00773-Cantabria, PS09/01286-León, PS09/01903-Valencia, PS09/02078-Huelva, PS09/01662-Granada, PI11/01403, PI11/01889-FEDER, PI11/00226, PI11/01810, PI11/02213, PI12/00488, PI12/00265, PI12/01270, PI12/00715, PI12/00150, PI14/01219, PI14/0613, PI15/00069, PI15/00914, PI15/01032, PI11/01810, PI14/01219, PI11/02213, PIE16/00049, PI17/01179, PI17-00092), by the Fundación Marqués de Valdecilla (API 10/09), by the Red Temática de Investigación del Cáncer (RTICC) del ISCIII (RD12/0036/0036), by the Junta de Castilla y León (LE22A10-2), by the Consejería de Salud of the Junta de Andalucía (PI-0571-2009, PI-0306-2011, salud201200057018tra), by the Conselleria de Sanitat of the Generalitat Valenciana (AP_061/10), by the Recercaixa (2010ACUP00310), by the Regional Government of the Basque Country, by the Consejería de Sanidad de la Región de Murcia, by the European Commission grants FOOD-CT-2006-036224-HIWATE, by the Spanish Association Against Cancer (AECC) Scientific Foundation – grant GCTRA18022MORE, by the Catalan Government-Agency for Management of University and Research Grants (AGAUR) grants 2014SGR647, 2014SGR850 and 2017SGR723. Sample collection of this work was supported by the Xarxa de Bancs de Tumors de Catalunya sponsored by “Pla Director d'Oncología de Catalunya (XBTC)”, “Plataforma Biobancos PT13/0010/0013” and ICOBIOBANC, sponsored by the Catalan Institute of Oncology. Mireia Obón-Santacana received a post-doctoral fellowship from the Spanish Association Against Cancer (AECC) Scientific Foundation (POSTD037OBÓN). We acknowledge support from the Spanish Ministry of Science and Innovation through the “Centro de Excelencia Severo Ochoa 2019-2023” Program (CEX2018-000806-S), and support from the Generalitat de Catalunya through the CERCA Program. Funders had no role in the design and conduct of the study; collection, analysis, and interpretation of the data; and preparation, review, or approval of the manuscript.},
publisher = {Elsevier},
publisher = {Clinical Nutrition (Edinburgh), 2021, 40(4), 1537-1545},
title = {Consumption of ultra-processed foods and drinks and colorectal, breast, and prostate cancer},
author = {Romaguera, Dora and Fernández-Barrés, Sílvia and Gracia-Lavedán, Esther and Vendrell, Eva and Azpiri, Mikel and Ruiz-Moreno, Emma and Martín, Vicente and Gómez Acebo, Inés and Obón, Mireia and Molinuevo, Amaia and Fresán, Ujué and Molina-Barceló, Ana and Olmedo-Requena, Rocío and Tardón García, Adonina and Alguacil, Juan and Solans, Marta and Huerta, Jose M. and Ruiz-Dominguez, José Manuel and Aragonés, Nuria and Fernández-Villa, Tania and Dierssen Sotos, Trinidad and Moreno, Victor and Guevara, Marcela and Vanaclocha-Espi, Mercedes and Lozano-Lorca, Macarena and Fernández-Tardón, Guillermo and Castaño-Vinyals, Gemma and Pérez-Gómez, Beatriz and Molina, Antonio J. and Llorca Díaz, Francisco Javier and Gil, Leire and Castilla, Jesús and Pollán, Marina and Kogevinas, Manolis and Amiano, Pilar},
}