@article{10902/35122, year = {2024}, url = {https://hdl.handle.net/10902/35122}, abstract = {The present study evaluates the effects of vaccination with Brucella melitensis strains Rev 1 AeryCD and Rev 1 on the reproductive system of male goats. Three groups, each of them consisting of 15 six-month-old brucellosis-free male goats, were studied. The first group was vaccinated with the Rev 1 AeryCD strain, the second group received Rev 1 and the third group was inoculated with sterile physiological saline solution. The dose of both strains was of 1 × 109 CFU/ml. Over the course of the five months of this study, three males from each group were euthanized every month. Their reproductive tracts, spleens, and lymph nodes were collected to analyze serology, bacteriologA PCR, histology, and immunohistochemistry. Results show that vaccination with B. melitensis strains Rev 1 AeryCD and Rev 1 does not harm the reproductive system of male goats. Strain B. melitensis Rev 1 AeryCD displayed a lower capacity to colonize the reproductive tract than strain Rev 1, which was attributed to its limited catabolic action toward erythritol.}, abstract = {The present study evaluates the effects of vaccination with Brucella melitensis strains Rev 1 AeryCD and Rev 1 on the reproductive system of male goats. Three groups, each of them consisting of 15 six-month-old brucellosis-free male goats, were studied. The first group was vaccinated with the Rev 1 AeryCD strain, the second group received Rev 1 and the third group was inoculated with sterile physiological saline solution. The dose of both strains was of 1 × 109 CFU/ml. Over the course of the five months of this study, three males from each group were euthanized every month. Their reproductive tracts, spleens, and lymph nodes were collected to analyze serology, bacteriology PCR, histology, and immunohistochemistry. Results show that vaccination with B. melitensis strains Rev 1 AeryCD and Rev 1 does not harm the reproductive system of male goats. Strain B. melitensis Rev 1 AeryCD displayed a lower capacity to colonize the reproductive tract than strain Rev 1, which was attributed to its limited catabolic action toward erythritol.}, organization = {Funding:This work was partially supported by project: “Evaluation of encapsulated proteic immunogens to prevent caprine brucellosis” Programa de Apoyo a Proyectos de Investigación e Innovación Tecnológica (PAPIIT) IT201517. I.A. López Vásquez received a scholarship from CONACYT.}, publisher = {Asociación Argentina de Microbiología}, publisher = {Revista Argentina de Microbiología, 2024, 56, 270-275}, title = {Effects of vaccination with Brucella melitensis, strains Rev 1 AeryCD and Rev 1, on the reproductive system of young male goats}, author = {López Vásquez, Isauro Alejandro and Palomares Resendiz, Erika Gabriela and Gutiérrez Hernández, José Luis and Garrido Fariña, Germán Isauro and Tórtora Pérez, Jorge Luis and Olmos Espejel, José de Jesús and Hernández Castro, Rigoberto and Sangari García, Félix Javier and Suárez Güemes, Francisco and Díaz Aparicio, Efrén}, }