@article{10902/34809, year = {2020}, url = {https://hdl.handle.net/10902/34809}, abstract = {Introduction: Clinical and experimental evidence supports the presence of several gender differences in the pain experience. Areas covered: The current paper discusses biological, psychological, emotional, and social differences according to gender and their relevance to TTH. Gender differences have also been observed in men and women with tension-type headache and they should be considered by clinicians managing this condition. It appears that multimodal treatment approaches lead to better outcomes in people with tension-type headache; however, management of tension-type headache should consider these potential gender differences. Different studies have observed the presence of complex interactions between tension-type headache, emotional stress, sleep, and burden and that these interactions are different between men and women. Expert opinion: Based on current results, the authors hypothesize that treatment of men with tension-type headache should focus on the improvement of sleep quality and the level of depression whereas treatment of women with TTH should focus on nociceptive mechanisms and emotional/stressful factors. Future trials should investigate the proposed hypotheses.}, publisher = {Taylor & Francis}, publisher = {Expert Review of Neurotherapeutics, 2020, 20(7), 659-666}, title = {Current perspectives on sex differences in tension-type headache}, author = {Fuensalida-Novo, Stella and Jiménez-Antona, Carmen and Benito-González, Elena and Cigarán-Méndez, Margarita and Parás Bravo, Paula and Fernández-De-Las-Peñas, César}, }