@article{10902/32109,
year = {2024},
url = {https://hdl.handle.net/10902/32109},
abstract = {Background and objectives: Recurrent isolated pancreatic metastasis from Renal Cell Carcinoma (RCC) after pancreatic resection is rare. The purpose of our study is to describe a series of cases of relapse of pancreatic metastasis from renal cancer in the pancreatic remnant and its surgical treatment with a repeated pancreatic resection, and to analyse the results of both overall and disease-free survival. Methods: Multicenter retrospective study of patients undergoing pancreatic resection for RCC pancreatic metastases, from January 2010 to May 2020. Patients were grouped into two groups depending on whether they received a single pancreatic resection (SPS) or iterative pancreatic resection. Data on short and long-term outcome after pancreatic resection were collected. Results: The study included 131 pancreatic resections performed in 116 patients. Thus, iterative pancreatic surgery (IPS) was performed in 15 patients. The mean length of time between the first pancreatic surgery and the second was 48.9 months (95 % CI: 22.2-56.9). There were no differences in the rate of postoperative complications. The DFS rates at 1, 3 and 5 years were 86 %, 78 % and 78 % vs 75 %, 50 % and 37 % in the IPS and SPS group respectively (p = 0.179). OS rates at 1, 3, 5 and 7 years were 100 %, 100 %, 100 % and 75 % in the IPS group vs 95 %, 85 %, 80 % and 68 % in the SPS group (p = 0.895). Conclusion: Repeated pancreatic resection in case of relapse of pancreatic metastasis of RCC in the pancreatic remnant is justified, since it achieves OS results similar to those obtained after the first resection.},
organization = {This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.},
publisher = {Blackwell Scientific},
publisher = {Surgical Oncology, 2024,  52, 102039},
title = {Repeated pancreatic resection for pancreatic metastases from renal cell Carcinoma: a Spanish multicenter study (PANMEKID)},
author = {Rojas-Holguín, Adela and Fondevila-Campo, Constantino and Sanjuanbenito, Alfonso and Fabregat-Prous, Joan and Secanella-Medayo, Luís and Rotellar-Sastre, Fernando and Pardo-Sánchez, Fernando and Prieto-Calvo, Mikel and Marín-Ortega, Héctor and Sánchez-Cabús, Santiago and Díez-Valladares, Luis and Alonso-Casado, Óscar and González-Serrano, Carmen and Rodríguez Sanjuán, Juan Carlos and García-Plaza, Gabriel and Jaén-Torrejimeno, Isabel and Suárez-Muñoz, Miguel Ángel and Becerra-Massare, Antonio and Senra-del Río, Paula and Pando, Elizabeth},
}