@article{10902/32067, year = {2020}, url = {https://hdl.handle.net/10902/32067}, abstract = {Introduction: the goal of this study was to determine the prevalence of hepatitis C virus (HCV) infection in patients with non-affective psychotic disorders and to compare it with population-based data. Material and methods: an observational study was performed that measured anti-HCV antibodies (HCV-RNA in case of seropositivity) in 425 serum samples from patients with non-affective psychosis. Eight patients were positive for anti-HCV (1.9 %) and five had detectable HCV-RNA (1.2 %). The prevalence of viremia was significantly higher than in the general population (OR: 5.4; 95 % CI: 1.9-14.6). Conclusions: patients with non-affective psychotic disorder have a higher prevalence of active infection than that of the general population and should undergo systematic screening.}, abstract = {Introducción: nuestro objetivo fue determinar la prevalencia de infección por virus de la hepatitis C (VHC) en pacientes con trastornos psicóticos no afectivos y compararla con los datos poblacionales. Material y métodos: se realizó un estudio observacional mediante la determinación de anti-VHC (RNA-VHC en los seropositivos) sobre 425 muestras séricas de pacientes con psicosis no afectiva. Resultados: ocho pacientes presentaron anti-VHC positivo (1,9 %) y cinco, RNA-VHC detectable (1,2 %). La prevalencia de viremia fue significativamente mayor que la de la población general (OR 5,4; IC 95 %: 1,9-14,6). Conclusiones: los pacientes con trastorno psicótico no afectivo presentan una prevalencia de infección activa superior a la población general y deberían ser objeto de un cribado sistemático.}, organization = {We are particularly grateful to the patients and to Biobanco Valdecilla (PT17/0015/0019), included in the Red Nacional de Biobancos (Spanish National Biobank Network), for their collaboration. The samples and data of the patients included in this study were provided by Biobanco Valdecilla (PTll/0015/0019) and were processed according to standard procedures. This study was partly supported by an Instituto Carlos III grant (Proyectos Integrados de Excelencia; PIE15/00079 and PI15/02138). The funding source played no role in study design, data collection and analysis, publishing decision or manuscript preparation.}, publisher = {Arán}, publisher = {Revista Española de Enfermedades Digestivas, 2020, 112(7), 550-554}, title = {Prevalence of hepatitis C in patients with non-affective psychotic disorders}, author = {Cuadrado Lavín, Antonio and Cabezas González, Joaquín and Llerena Santiago, Susana and Nieves Salceda, Juan and Fortea Ormaechea, José Ignacio and Crespo Facorro, Benedicto and Crespo García, Javier}, }