@article{10902/31447,
year = {2017},
url = {https://hdl.handle.net/10902/31447},
abstract = {Advanced single molecular analysis is a key stepping stone for the rapid sensing and characterization of biomolecules. This will only be made possible through the implementation of versatile platforms, with high sensitivities and the precise control of experimental conditions. The presented work details an advancement of this technology, through the development of a low-noise Pyrex/silicon nitride/gold nanopore platform. The nanopore is surrounded by a plasmonic bullseye structure and provides targeted and controllable heating via laser irradiation, which is directed toward the center of the pore. The device architecture is investigated using multiwavelength laser heating experiments and 'individual DNA molecules are detected under controlled heating. The plasmonic features, optimized through numerical simulations, are tuned to the wavelength of incident light, ensuring a platform that provides substantial heating with high signal-to-noise.},
organization = {Research by CRC and PA was supported by Canary Islands CIE: Tricontinental Atlantic Campus. PA acknowledges “Programa “Viera y Clavijo” de la Agencia Canaria de Investigación, Innovación y Sociedad de la Información (ACIISI)”, and the University of las Palmas de Gran Canaria (ULPGC) for their support. J.B.E. acknowledges support from the BBSRC and ERC (Starting Investigator Grant). A.I. acknowledges the support of the IC Research Fellowship. K.B.K. acknowledge that this research was supported by the Pioneer Research Center Program through the National Research Foundation of Korea funded by the Ministry of Science, ICT & Future Planning (2012-0009563). S.A.M. would like to acknowledge the EPRSC Reactive Plasmonics Programme, ONR Global, and the Lee Lucas Chair in Physics.},
publisher = {American Chemical Society},
publisher = {ACS Photonics, 2017, 4(11), 2835-2842},
title = {Low-noise plasmonic nanopore biosensors for single molecule detection at elevated temperatures},
author = {Crick, Colin R. and Albella Echave, Pablo and Kim, Hyung-Jun and Ivanov, Aleksandar P. and Kim, Ki-Bum and Maier, Stefan A. and Edel, Joshua B.},
}