@article{10902/31209,
year = {2020},
url = {https://hdl.handle.net/10902/31209},
abstract = {We aimed to evaluate lung cancer survival in never-smokers, both overall and specifically by sex, exposure to residential-radon, age, histological type, and diagnostic stage.
We included lung cancer cases diagnosed in a multicentre, hospital-based, case-control-study of never-smoker patients, diagnosed from January-2011 to March-2015 (Lung Cancer Research In Never Smokers study).

369 never-smokers (79% women; median age 71 years; 80% adenocarcinoma; 66% stage IV) were included. Median overall survival, and at one, 3 and 5 years of diagnosis was 18.3 months, 61%, 32% and 22%, respectively. Higher median survival rates were obtained for: younger age, adenocarcinoma, actionable mutations, and earlier-stage at diagnosis. Higher indoor radon showed a higher risk of death in multivariate analysis.
Median lung cancer survival in never-smokers seems higher than that in ever-smokers. Patients with actionable mutations have a significantly higher survival. Higher indoor-radon exposure has a negative effect on survival},
organization = {This paper was funded by the following competitive research grants awarded to the individual case-control studies, which are part of this pooled study: Galician Regional Authority (Xunta de Galicia): 10CSA208057PR “Risk factors of lung cancer in never smokers: a multicentre case-control study in the Northwest of Spain.” 2010. Spain; Carlos III Institute of Health (Instituto de Salud Carlos III), Ministry of Science and Innovation of Spain, grant number PI03/1248. 2003. Spain; Carlos III Institute of Health (grant FIS 92/0176) and the Galician Regional Health Authority (grant XUGA 91010). 1992. Spain; Galician Regional Authority: grant number XUGA 208001B93. 1993; Carlos III Institute of Health, Ministry of Science and Innovation of Spain, grant number PI13/01765. 2013. Spain; ISCIII - PI15/01211 - Cofinanciado FEDER. Spain.},
organization = {This paper was funded by the following competitive research grants awarded to the individual case-control studies, which are part of this pooled study: 
• Galician Regional Authority (Xunta de Galicia): 10CSA208057PR “Risk factors of lung cancer in never smokers: a multicentre case-control study in the Northwest of Spain.” 2010. Spain. 
• Carlos III Institute of Health (Instituto de Salud Carlos III), Ministry of Science and Innovation of Spain, grant number PI03/1248. 2003. Spain. 
• Carlos III Institute of Health (grant FIS 92/0176) and the Galician Regional Health Authority (grant XUGA 91010). 1992. Spain. 
• Galician Regional Authority: grant number XUGA 208001B93. 1993. 
• Carlos III Institute of Health, Ministry of Science and Innovation of Spain, grant number PI13/01765. 2013. Spain. 
• ISCIII - PI15/01211 - Cofinanciado FEDER. Spain.},
publisher = {Elsevier Science Ireland},
publisher = {Cancer Letters, 2020, 487, 21-26 - (CORRIGENDUM), 2020, 493, 10},
title = {Lung cancer survival in never-smokers and exposure to residential radon: results of the LCRINS study},
author = {Casal-Mouriño, Ana and Ruano-Ravina, Alberto and Torres-Durán, María and Parente-Lamelas, Isaura and Provencio-Pulla, Mariano and Castro-Añón, Olalla and Vidal-García, Iria and Pena-Álvarez, Carolina and Abal-Arca, José and Piñeiro-Lamas, María and Fuente Merino, Ismael and Fernández-Villar, Alberto and Abdulkader, Ihab and Valdés-Cuadrado, Luis and Barros-Dios, Juan Miguel and Pérez-Ríos, Mónica},
}