@article{10902/29039,
year = {2022},
url = {https://hdl.handle.net/10902/29039},
abstract = {The purpose of the study was to analyze the relationship between the high-sensitivity troponin T levels in patients with confirmed influenza virus infection and its severity determined by mortality during the care process. In addition, a high-sensitivity troponin T cut-off value was sought to allow us to a safe discharge from the emergency department. An analytical retrospective observational study was designed in which high-sensitivity troponin T is determined as an exposure factor, patients are followed until the resolution of the clinical picture, and the frequency of mortality is analyzed. We included patients ? 16 years old with confirmed influenza virus infection and determination of high-sensitivity troponin T. One hundred twenty-eight patients were included (96.9% survivors, 3.1% deceased). Mean and median blood levels of high-sensitivity troponin T of survivors were 26.2 ± 58.3 ng/L and 14.5 ng/L (IQR 16 ng/L), respectively, and were statistically different when compared with those of the deceased patients, 120.5 ± 170.1 ng/L and 40.5 ng/L (IQR 266.5 ng/L), respectively, p = 0.012. The Youden index using mortality as the reference method was 0.76, and the cut-off value associated with this index was 24 ng/L (sensitivity 100%, specificity 76%, NPV 100%, PPV 4%) with AUC of 88,8% (95% CI: 79.8?92.2%), p < 0.001. We conclude that high-sensitivity troponin T levels in confirmed virus influenza infection are a good predictor of mortality in our population, and this predictor is useful for safely discharging patients from the emergency department.},
publisher = {Basel: MDPI AG},
publisher = {Journal of Personalized Medicine 2022, 12, 520},
title = {High-sensitivity troponin T: a potential safety predictive biomarker for discharge from the emergency department of patients with confirmed influenza},
author = {Tazón Varela, Manuel Antonio and Ortiz de Salido-Menchaca, Jon Ortiz and Muñoz Cacho, Pedro and Iriondo-Bernabeu, Enara and Martos-Almagro, María Josefa and Lavín-López, Emma and Vega-Zubiaur, Ander and Escalona-Canal, Edgar José and Alcalde-Díez, Iratxe and Gómez-Vildosola, Carmen and Belzunegui-Gárate, Ainhoa and Espinoza-Cuba, Fabiola and López-Cejuela, José Antonio and García-García, Alba and Torrejón-Cereceda, Alejandro and Nisa-Martínez, Elena Sabina and Moreira Nieto, Diana and Hellín-Mercadal, Cintia and García-Caballero, Ander and Alonso Valle, Héctor},
}