@article{10902/2580,
year = {2012},
month = {10},
url = {http://hdl.handle.net/10902/2580},
abstract = {This work reports on the implementation of different absorption micro-filters based on a dye-doped hybrid organic-inorganic xerogel polymeric material synthesized by the sol-gel process. Microstructures containing eight different filter widths were fabricated in polydimethylsiloxane (PDMS), bonded to glass substrates and filled with the corresponding dye doped polymeric material by a soft lithography approach. The filtering capacity as a function of dye concentration and filter width was studied and revealed a linear dependence with both parameters, as expected according to the Beer-Lambert law. Zero passband transmittance values and relatively sharp stopband regions were achieved with all the filters, also showing rejection levels between −6 dB and −55 dB. Finally, such filters were monolithically integrated into a disposable fluorescence-based photonic lab-on-a-chip (PhLoC) approach. Calibration curves carried out with a model fluorophore target analyte showed an over two-fold increase in sensitivity and a thirty-fold decrease of the limit of detection (LOD) compared with the values recorded using the same PhLoC system but without the polymeric filter structure. The results presented herein clearly indicate the feasibility of these xerogel-based absorbance filtering structures for being applied as low-cost optical components that can be easily incorporated into disposable fluorescence-based photonic lab on a chip systems.},
organization = {The research leading to these results has received funding from the European Research Council under the European Community's Seventh Framework Programme (FP7/2007-2013) / ERC grant agreement n° 209243 and from project ref. TEC2010-17274 (Spanish ministry of Economy and Competitivity). The authors would like to thank Dr. Manuel Gutiérrez-Capitán, from IMB-CNM (CSIC) and Dr. Magarita Darder from ICMM (CSIC), for their assistance with the FT-IR and the 29Si-NMR spectroscopic analysis, respectively.},
publisher = {The Optical Society (OSA)},
publisher = {Optics Express, 2012, 20(21), 23700-23719},
title = {Development and integration of xerogel polymeric absorbance micro-filters into lab-on-chip systems},
author = {Carregal Romero, Ester and Fernández Sánchez, César and Eguizabal Aguado, Alma and Demming, Stefanie and Büttgenbach, Stephanus and Llobera Adán, Andreu},
}