@article{10902/24459,
year = {2021},
url = {http://hdl.handle.net/10902/24459},
abstract = {Aim: The aim of this study was to determine the usefulness of COVID-GRAM and CURB-65 scores as predictors of the severity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in Caucasian patients.

Methods: This was a retrospective observational study including all adults with SARS-CoV-2 infection admitted to Hospital Universitario Marqués de Valdecilla from February to May 2020. Patients were stratified according to COVID-GRAM and CURB-65 scores as being at low-medium or high risk of critical illness. Univariate analysis, multivariate logistic regression models, receiver operating characteristic curve, and area under the curve (AUC) were calculated.

Results: A total of 523 patients were included (51.8% male, 48.2% female; mean age 65.63 years (standard deviation 17.89 years)), of whom 110 (21%) presented a critical illness (intensive care unit admission 10.3%, 30-day mortality 13.8%). According to the COVID-GRAM score, 122 (23.33%) patients were classified as high risk; 197 (37.7%) presented a CURB-65 score ?2. A significantly greater proportion of patients with critical illness had a high COVID-GRAM score (64.5% vs 30.5%; P < 0.001). The COVID-GRAM score emerged as an independent predictor of critical illness (odds ratio 9.40, 95% confidence interval 5.51-16.04; P < 0.001), with an AUC of 0.779. A high COVID-GRAM score showed an AUC of 0.88 for the prediction of 30-day mortality, while a CURB-65 ?2 showed an AUC of 0.83.

Conclusions: The COVID-GRAM score may be a useful tool for evaluating the risk of critical illness in Caucasian patients with SARS-CoV-2 infection. The CURB-65 score could be considered as an alternative.},
publisher = {Elsevier},
publisher = {Int J Infect Dis
. 2021 Jul;108:282-288},
title = {Usefulness of the COVID-GRAM and CURB-65 scores for predicting severity in patients with COVID-19},
author = {Armiñanzas Castillo, Carlos and Arnáiz de las Revillas Almajano, Francisco and Gutiérrez Cuadra, Manuel and Arnaiz García, Ana María and Fernández Sampedro, Marta and González-Rico, Claudia and Ferrer, Diego and Mora, Víctor and Suberviola, Borja and Latorre, Maite and Calvo, Jorge and Olmos Martínez, José Manuel and Cifrián Martínez, José Manuel and Fariñas Álvarez, María del Carmen},
}