@article{10902/23951,
year = {2021},
url = {http://hdl.handle.net/10902/23951},
abstract = {Introduction: Recent studies suggest a role of adipokines in the pathogenesis of hidradenitis suppurativa (HS). Omentin-1 and apelin are two recently identified adipokines that have been involved in the regulation of metabolic and inflammatory responses.

Aim: To investigate serum omentin-1 and apelin levels in patients with HS and to assess their associations with metabolic parameters, disease severity and HS risk.

Material and methods: This case-control study included 139 non-diabetic individuals (78 HS patients and 61 ageand sex-matched controls). Serum concentrations of omentin-1 and apelin and the homeostasis model assessment of insulin resistance (HOMA-IR) were measured in all participants.

Results: Serum omentin-1 concentrations were significantly higher in HS patients compared to controls, whereas apelin serum levels did not significantly differ between both groups. These differences in omentin-1 concentrations remained significant even after adjusting for age, sex, and body mass index (BMI). The results of logistic regression analysis showed that increased omentin-1 plasma levels were an independent risk factor for HS. However, we found no association between serum levels of both omentin-1 and apelin with HS severity.

Conclusions: Our results show that patients with HS have raised omentin-1 serum levels, which are associated with HS risk.},
publisher = {Termedia},
publisher = {Postepy Dermatol Alergol
. 2021 Jun;38(3):450-454},
title = {Evaluation of serum omentin-1 and apelin concentrations in patients with hidradenitis suppurativa},
author = {González López, Marcos Antonio and Ocejo Viñals, Javier Gonzalo and Mata, Cristina and Díaz, Diego and Guiral, Sandra and Portilla, Virginia and Corrales Martínez, Alfonso and González Vela, María del Carmen and González-Gay Mantecón, Miguel Ángel and Blanco Alonso, Ricardo and Hernández Hernández, José Luis},
}