@conference{10902/18324, year = {2019}, month = {7}, url = {http://hdl.handle.net/10902/18324}, abstract = {Optical Coherence Tomography (OCT) is nowadays being widely employed as a diagnostic tool for skin cancer. It can produce feedback on tissue morphology alterations produced by different pathologies. OCT images are mainly produced by differences in refractive index and attenuation coefficient, providing in-depth information. Intensity OCT images display the effect of tissue alterations on backscattered light, but it does not represent real physical magnitude. In a number of occasions, morphology alteration events within the same tissue type, produce intensity variations in OCT images that can be misclassified as different tissue component. The estimation of depth-resolved attenuation coefficient improves tissue contrast, helping to identify tissue identity and isolating the effect of disordered structures of the same tissue. The proposed methodology shows that melanoma and Basal Cell Carcinoma (BCC) pathologies exhibit different optical parameters in depth. This enhances the identification of subsurface skin features.}, organization = {This research was funded FIS2010-19860 (DA2TOI), TEC2016-76021-C2-2-R (SENSA), DTS17-00055 (FUSIODERM), INNVAL 16/02 (DICUTEN), INNVAL 18/23 (DAPATOO) and co-funded with FEDER funds. This work has been developed thanks to the collaboration of the members of Dermatology Service at Marqués de Valdecilla University Hospital.}, publisher = {SPIE Society of Photo-Optical Instrumentation Engineers-}, publisher = {The Optical Society (OSA)}, publisher = {Eusebio Real, Gema Pérez Paredes, José M. López Higuera, Olga M. Conde, "Depth-resolved attenuation coefficient estimation for skin cancer assessment with optical coherence tomography," in European Conference on Biomedical Optics: Optical Coherence Imaging Techniques and Imaging in Scattering Media III, edited by Maciej Wojtkowski, Stephen A. Boppart, Wang-Yuhl Oh, Vol. 11078 of Proceedings of SPIE-OSA Biomedical Optics, 1107812, (2019)}, title = {Depth-resolved attenuation coefficient estimation for skin cancer assessment with Optical Coherence Tomography}, author = {Real Peña, Eusebio and Pérez Paredes, Gema and López Higuera, José Miguel and Conde Portilla, Olga María}, }