@article{10902/12790,
year = {2018},
url = {http://hdl.handle.net/10902/12790},
abstract = {Residential radon exposure is a serious public health concern, and as such appears in the recommendations of European Code Against Cancer. The objective of this study was to assess the association between residential radon levels and mortality due to different types of cancer, using misaligned data analysis techniques. Mortality data (observed cases) for each of the 313 Galician municipalities were drawn from the records of the National Statistics Institute for the study period (1999?2008). Expected cases were computed using Galician mortality rates for 14 types of malignant tumors as reference, with a total of 56,385 deaths due to the tumors analyzed. The effect estimates of indoor radon (3371 sampling points) were adjusted for sociodemographic variables, altitude, and arsenic topsoil levels (1069 sampling points), using spatial/geostatistical models fitted with stochastic partial differential equations and integrated nested Laplace approximations. Thesemodels are capable of processing misaligned data. The results showed a statistical association between indoor radon and lung, stomach and brain cancer inwomen in Galicia. Apart fromlung cancer (relative risk (RR)=1.09), inwhich a twofold increase in radon exposure led to a 9% rise inmortality, the association was particularly relevant in stomach (RR=1.17) and brain cancer (RR=1.28). Further analytical epidemiologic studies are needed to confirm these results, and an assessment should be made of the advisability of implementing interventions targeting such exposure in higher-risk areas.},
organization = {The studywas partially supported by research grants fromthe Carlos
III Health Institute (PI4CIII/50) and Spanish Health Research Fund (FIS
PI11/00871).Mortality data were supplied by the Spanish National Statistics
Institute in accordance with a specific confidentiality protocol.},
publisher = {Elsevier},
publisher = {Science of the Total Environment 610-611 (2018) 1125-1132},
title = {Residential radon and cancer mortality in Galicia, Spain},
author = {López Abente, Gonzalo and Núñez, Olivier and Fernández Navarro, Pablo and Barros Dios, Juan M. and Martín Méndez, Iván and Bel Lan, Alejandro and Locutura, Juan and Quindós Poncela, Luis Santiago and Sainz Fernández, Carlos and Ruano Ravina, Alberto},
}