@article{10902/11831,
year = {2017},
url = {http://hdl.handle.net/10902/11831},
abstract = {In tetrapods the digit pattern has evolved to adapt to distinct locomotive strategies. The
number of digits varies between species or even between hindlimb and forelimb within
the same species. These facts illustrate the plasticity of embryonic limb autopods. Sox9
is a precocious marker of skeletal differentiation of limb mesenchymal cells. Its pattern
of expression in the developing limb has been widely studied and reflects the activity
of signaling cascades responsible for skeletogenesis. In this assay we stress previously
overlooked differences in the pattern of expression of Sox9 in limbs of avian, mouse
and turtle embryos which may reflect signaling differences associated with distinct limb
skeletal morphologies observed in these species. Furthermore, we show that Sox9 gene
expression is higher and maintained in the interdigital region in species with webbed
digits in comparison with free digit animals.},
publisher = {Frontiers},
publisher = {Front. Cell Dev. Biol., 23 March 2017},
title = {Sox9 Expression in Amniotes: Species-Specific Differences in the Formation of Digits},
author = {Montero Simón, Juan Antonio and Lorda Diez, Carlos Ignacio and Francisco Morcillo, Javier and Chimal Monroy, Jesús and García-Porrero Pérez, Juan Antonio and Hurlé González, Juan M.},
}