@article{10902/11528,
year = {2017},
url = {http://hdl.handle.net/10902/11528},
abstract = {Solid organ transplant (SOT) recipients are especially at risk of developing infections by multidrug resistant (MDR) Gram-negative bacilli (GNB), as they are frequently exposed to antibiotics and the healthcare setting, and are regulary subject to invasive procedures. Nevertheless, no recommendations concerning prevention and treatment are available. A panel of experts revised the available evidence; this document summarizes their recommendations: (1) it is important to characterize the isolate´s phenotypic and genotypic resistance profile; (2) overall, donor colonization should not constitute a contraindication to transplantation, although active infected kidney and lung grafts should be avoided; (3) recipient colonization is associated with an increased risk of infection, but is not a contraindication to transplantation; (4) different surgical prophylaxis regimens are not recommended for patients colonized with carbapenem-resistant GNB; (5) timely detection of carriers, contact isolation precautions, hand hygiene compliance and antibiotic control policies are important preventive measures; (6) there is not sufficient data to recommend intestinal decolonization; (7) colonized lung transplant recipients could benefit from prophylactic inhaled antibiotics, specially for Pseudomonas aeruginosa; (8) colonized SOT recipients should receive an empirical treatment which includes active antibiotics, and directed therapy should be adjusted according to susceptibility study results and the severity of the infection.},
organization = {J.T.S. holds a research contract from the Fundación para la Formación e Investigación de los Profesionales de la Salud de Extremadura (FundeSalud), Instituto de Salud Carlos III. M.F.R. holds a clinical research contract “Juan Rodés” (JR14/00036) from the Spanish Ministry of Economy and Competitiveness, Instituto de Salud Carlos III.},
publisher = {Elsevier},
publisher = {Transplantation Reviews,  2018, 32(1), 36-57},
title = {Management of multidrug
resistant Gram-negative bacilli infections in solid organ transplant recipients:
SET/GESITRA-SEIMC/REIPI recommendations},
author = {Aguado García, José María and Silva, J.T. and Fernández Ruiz, M. and Cordero, E. and Fortún, J. and Gudiol, C. and Martínez Martínez, L. and Vidal, E. and Almenar, L. and Almirante, B. and Cantón, R. and Carratalá Fernández, Jordi and Caston, J.J. and Cercenado, E. and Cervera, C. and Cisneros, J.M. and Crespo Leiro, M.G. and Cuervas Mons, V. and Elizalde Fernández, J. and Fariñas Álvarez, María del Carmen},
}